Fabrication and drug release study of double-layered microparticles of various sizes

• Main Authors: Lee, Wei Li, Seh, Yi Chuan, Widjaja, Effendi, Chong, Han Chung, Tan, Nguan Soon, Loo, Say Chye Joachim
• Other Authors: School of Materials Science & Engineering
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Engineering::Materials::Biomaterials
• Online Access: https://hdl.handle.net/10356/99614; http://hdl.handle.net/10220/17460
• Institution: Nanyang Technological University

Double-layered microparticles, composed of poly(D,L-lactide-co-glycolide) (50:50) (PLGA) core and poly(L-lactide) (PLLA) shell, of controllable sizes ranging from several hundred microns to few microns were fabricated using a one-step solvent evaporation method. Metoclopramide monohydrochloride mono...