Direct electrochemical reduction of single-layer graphene oxide and subsequent functionalization with glucose oxidase

A direct electrochemical method to reduce single-layer graphene oxide (GO) adsorbed on the 3-aminopropyltriethoxysilane (APTES)-modified conductive electrodes is proposed. The reduced GO adsorbed on glassy carbon electrode was modified with glucose oxidase (GOx) by covalent bonding via a polymer gen...

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Bibliographic Details
Main Authors: Wang, Zhijuan, Zhou, Xiaozhu, Zhang, Juan, Boey, Freddy Yin Chiang, Zhang, Hua
Other Authors: School of Materials Science & Engineering
Format: Article
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/99644
http://hdl.handle.net/10220/8558
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Institution: Nanyang Technological University
Language: English
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Summary:A direct electrochemical method to reduce single-layer graphene oxide (GO) adsorbed on the 3-aminopropyltriethoxysilane (APTES)-modified conductive electrodes is proposed. The reduced GO adsorbed on glassy carbon electrode was modified with glucose oxidase (GOx) by covalent bonding via a polymer generated by electrografting N-succinimidyl acrylate (NSA). The direct electron transfer between the electrode and GOx molecules was realized. The bioactivity of GOx maintains very well on the electrode. The thus-prepared GOx-modified electrode was successfully used to detect glucose.