cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity
The first successful generation of cis-homoenolate equivalents from cis-enals under the catalysis of N-heterocyclic carbenes (NHCs) has been realized. The cis-homoenolate intermediates undergo effective reactions with α,β-unsaturated imines to afford chiral cyclic ketone products. Compared to the tr...
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sg-ntu-dr.10356-996942020-03-07T12:34:48Z cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity Chen, Xingkuan Fang, Xinqiang Chi, Robin Yonggui School of Physical and Mathematical Sciences Physical and Mathematical Sciences The first successful generation of cis-homoenolate equivalents from cis-enals under the catalysis of N-heterocyclic carbenes (NHCs) has been realized. The cis-homoenolate intermediates undergo effective reactions with α,β-unsaturated imines to afford chiral cyclic ketone products. Compared to the trans-enals, cis-enals show different stereoselectivities and new reactivity patterns. 2013-11-08T06:12:07Z 2019-12-06T20:10:26Z 2013-11-08T06:12:07Z 2019-12-06T20:10:26Z 2013 2013 Journal Article Chen, X., Fang, X., & Chi, Y. R. (2013). cis-Enals in N-heterocyclic carbene-catalyzed reactions: distinct stereoselectivity and reactivity. Chemical Science, 4(6), 2613-2618. https://hdl.handle.net/10356/99694 http://hdl.handle.net/10220/17475 10.1039/c3sc50666e 173631 en Chemical science |
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Physical and Mathematical Sciences Chen, Xingkuan Fang, Xinqiang Chi, Robin Yonggui cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| description |
The first successful generation of cis-homoenolate equivalents from cis-enals under the catalysis of N-heterocyclic carbenes (NHCs) has been realized. The cis-homoenolate intermediates undergo effective reactions with α,β-unsaturated imines to afford chiral cyclic ketone products. Compared to the trans-enals, cis-enals show different stereoselectivities and new reactivity patterns. |
| author2 |
School of Physical and Mathematical Sciences |
| author_facet |
School of Physical and Mathematical Sciences Chen, Xingkuan Fang, Xinqiang Chi, Robin Yonggui |
| format |
Article |
| author |
Chen, Xingkuan Fang, Xinqiang Chi, Robin Yonggui |
| author_sort |
Chen, Xingkuan |
| title |
cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title_short |
cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title_full |
cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title_fullStr |
cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title_full_unstemmed |
cis-Enals in N-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| title_sort |
cis-enals in n-heterocyclic carbene-catalyzed reactions : distinct stereoselectivity and reactivity |
| publishDate |
2013 |
| url |
https://hdl.handle.net/10356/99694 http://hdl.handle.net/10220/17475 |
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1681047288142626816 |