The effect of salt on oligocation-induced chromatin condensation

• Main Authors: Korolev, Nikolay, Zhao, Yongqian, Allahverdi, Abdollah, Eom, Khee Dong, Nordenskiöld, Lars, Tam, James P.
• Other Authors: School of Biological Sciences
• Format: Article
• Language: English
• Published: 2013
• Subjects: DRNTU::Science::Biological sciences
• Online Access: https://hdl.handle.net/10356/99954; http://hdl.handle.net/10220/11030
• Institution: Nanyang Technological University

Condensation of model chromatin in the form of fully saturated 12-mer nucleosome arrays, induced by addition of cationic ligands (ε-oligolysines with charge varied from +4 to +11), was studied in a range of KCl concentrations (10–500 mM) using light scattering and precipitation assay titrations. The...