NMR binding and crystal structure reveal that intrinsically-unstructured regulatory domain auto-inhibits PAK4 by a mechanism different from that of PAK1

NMR binding and crystal structure reveal that intrinsically-unstructured regulatory domain auto-inhibits PAK4 by a mechanism different from that of PAK1

10.1016/j.bbrc.2013.07.047

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Bibliographic Details
Main Authors: Wang, W., Lim, L., Baskaran, Y., Manser, E., Song, J.
Other Authors: BIOLOGICAL SCIENCES
Format: Article
Published: 2014
Subjects:
Auto-inhibition
Intrinsically unstructured protein (IUP)
Isothermal titration calorimetry (ITC)
NMR spectroscopy
P21-activated kinases (PAKs)
X-ray crystallography
Online Access:http://scholarbank.nus.edu.sg/handle/10635/101228
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Institution: National University of Singapore

Internet

http://scholarbank.nus.edu.sg/handle/10635/101228

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