A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5] triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities

A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5] triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities

10.1016/j.ejmech.2013.06.051

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Bibliographic Details
Main Authors: Bera, H., Tan, B.J., Sun, L., Dolzhenko, A.V., Chui, W.-K., Chiu, G.N.C.
Other Authors: PHARMACY
Format: Article
Published: 2014
Subjects:
1,2,4-Triazolo[1,5-a][1,3,5]triazine
Anti-angiogenesis
Breast cancer
Mixed-type inhibition
SAR
Thymidine phosphorylase inhibitors
Online Access:http://scholarbank.nus.edu.sg/handle/10635/105597
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Institution: National University of Singapore
Description
Summary:10.1016/j.ejmech.2013.06.051

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