Practical synthesis of regioisomeric 5(7)-amino-6,7(4,5)-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazines

Practical synthesis of regioisomeric 5(7)-amino-6,7(4,5)-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazines

10.1016/j.tet.2007.10.046

Saved in:

Bibliographic Details
Main Authors:	Dolzhenko, A.V., Chui, W.-K.
Other Authors:	PHARMACY
Format:	Article
Published:	2014
Subjects:	1,2,4-Triazoles 5-Azapurines Fused 1,3,5-triazines Hydrazides Tautomerism Triazolotriazines
Online Access:	http://scholarbank.nus.edu.sg/handle/10635/106235
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

Similar Items

Synthesis and biological activity of fluorinated 7-aryl-2-pyridyl-6,7-dihydro[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-amines [1]
by: Dolzhenko, A.V., et al.
Published: (2014)

Fused heterocyclic systems with an s-triazine ring. 34. Development of a Practical Approach for the Synthesis of 5-Aza-isoguanines
by: Junaid, A., et al.
Published: (2021)

Synthesis and in vitro evaluation of 1,2,4-triazolo[1,5-a][1,3,5]triazine derivatives as thymidine phosphorylase inhibitors
by: Bera, H., et al.
Published: (2014)

A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5] triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities
by: Bera, H., et al.
Published: (2014)

Synthesis, in vitro evaluation of thymidine phosphorylase inhibitory activity, and in silico study of 1,3,5-triazin-2,4-dione and its fused analogues
by: Bera, H., et al.
Published: (2014)

SYNTHESIS OF 4,6-DIAMINO-1,2-DIHYDRO-1,3,5-TRIAZINES AS POTENTIAL BACTERIAL DIHYDROFOLATE REDUCTASE INHIBITORS
by: YANG XUAN
Published: (2017)

Synthesis and tautomerism study of 6-benzoylmethyl-1,3,5-triazin-2,4- diamine
by: Sachdeva, N., et al.
Published: (2014)

Pyrazolo[1,5-α][1,3,5]triazines (5-Aza-9-deazapurines): Synthesis and biological activity
by: Dolzhenko, A.V., et al.
Published: (2014)

5,5-Dimethyl-2-phenyl-4,5-dihydro-1,2,4-triazolo[1,5-a][1,3,5] triazin-7-amine
by: Dolzhenko, A.V., et al.
Published: (2014)

7,7-Dimethyl-2-phenyl-6,7-dihydro-1,2,4-triazolo[1,5-a][1,3,5] triazin-5-amine
by: Dolzhenko, A.V., et al.
Published: (2014)

Molecular and crystal structure of 7,7-dimethyl-2-pyridin-4-yl- 6,7-dihydro-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amine [1]
by: Dolzhenko A.V., et al.
Published: (2020)

Synthesis and antimicrobial activity of N 1-benzyl or N 1-benzyloxy-1,6-dihydro-1,3,5-triazine-2,4-diamines
by: Ma, X., et al.
Published: (2014)

Antifolate and antiproliferative activity of 6,8,10-triazaspiro[4.5]deca-6,8-dienes and 1,3,5-triazaspiro[5.5]undeca-1,3-dienes
by: Ma, X., et al.
Published: (2014)

2-Phenyl-7-(4-pyridylmethylamino)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5(4H) -one
by: Dolzhenko, A.V., et al.
Published: (2014)

Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1, 5-a][1,3,5]triazines as thymidine phosphorylase inhibitors
by: Sun, L., et al.
Published: (2014)

A convenient method for the synthesis of 7-amino-substituted 1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amines
by: Dolzhenko, A.V., et al.
Published: (2014)

7-(4-Fluorobenzylamino)-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5] triazin-5-amine methanol disolvate
by: Dolzhenko, A.V., et al.
Published: (2014)

Discovery of mixed type thymidine phosphorylase inhibitors endowed with antiangiogenic properties: Synthesis, pharmacological evaluation and molecular docking study of 2-thioxo-pyrazolo[1,5-a][1,3,5]triazin-4-ones. Part II
by: Bera, H., et al.
Published: (2014)

Synthesis of 5,7-diamino1,2,4 triazolo[1,2-a1,3,5 triazines via annulation of 1,3,5-triazine ring onto 3(5)-amino-1,2,4-triazoles
by: Dolzhenko, A.V., et al.
Published: (2014)

Synthesis of pyrazolo[1,5-a][1,3,5]triazine derivatives as inhibitors of thymidine phosphorylase
by: Sun, L., et al.
Published: (2014)

1,2,4-triazolo[1,5-a][1,3,5]triazines (5-azapurines): synthesis and biological activity
by: Dolzhenko, A.V., et al.
Published: (2014)

Derivatives of Pyrazolo[1,5-a][1,3,5]Triazines as Enzyme Inhibitors with Potential Therapeutic Value
by: SUN LINGYI
Published: (2013)

Synthesis and hererocyclizations of 3,4-dihydroquinazolin-2-yl guanidine in the search of new anticancer agents
by: Dolzhenko, A.V., et al.
Published: (2014)

Synthesis and in vitro evaluation of 2,4-diamino-1,3,5-triazine derivatives as neuronal voltage-gated sodium channel blockers
by: Ma, X., et al.
Published: (2014)

7-Dimethyl-amino-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amine methanol solvate
by: Dolzhenko, A.V., et al.
Published: (2014)

2,4,6-triphenyl-1,3,5-triazine based covalent organic frameworks for photoelectrochemical H2 evolution
by: Dai, Chunhui, et al.
Published: (2021)

Synthesis, anti-thymidine phosphorylase activity and molecular docking of 5-thioxo-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-ones
by: Bera, H., et al.
Published: (2014)

Synthesis of ethyl 6-aryl-4-oxo-4,6-dihydro-1(12)(13)H-pyrimido-[2′, 1′:4,5][1,3,5]triazino[1,2-a]benzimidazole-3-carboxylates
by: Dolzhenko, A.V., et al.
Published: (2014)

Synthesis and bioactivity study of 4,6-diamino-1,3,5-triazines
by: MA XIANG
Published: (2010)

Solid-phase synthesis and biological evaluation of 1, 3, 5-triazine derivatives
by: KONG KAH HOE
Published: (2010)

A new synthesis of 2,8-disubstituted pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidines
by: Dolzhenko, A.V., et al.
Published: (2014)

Synthesis and biological activity of fluorinated 7-benzylamino-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amines
by: Dolzhenko Anna V., et al.
Published: (2016)

8-Methyl-2-[4-(trifluoromethyl)phenyl]-8H-pyrazolo-[4,3-e][1,2,4] triazolo[1,5-c]pyrimidin-5-amine methanol disolvate
by: Dolzhenko, A.V., et al.
Published: (2014)

2,4,6-Triphenyl-1,3,5-Triazine Based Covalent Organic Frameworks for Photoelectrochemical H-2 Evolution
by: Dai, Chunhui, et al.
Published: (2022)

Regiospecific solid-phase synthesis of substituted 1,2,3-triazoles
by: Raghavendra, M.S., et al.
Published: (2014)

SYNTHESIS AND BIOLOGICAL EVALUATION OF THE DERIVATIVES OF 1,3,5-TRIAZIN-2,4-DIONES AND THEIR FUSED ANALOGUES.
by: HRIDAY BERA
Published: (2012)

Simple synthesis of 2-amino-4-(het)aryl-4,6-dihydro-1(3)(11)H-[1,3,5] triazino[2,1-b]quinazolin-6-ones [1]
by: Dolzhenko, A.V., et al.
Published: (2014)

Synthesis and biological activity of fluorinated 2-amino-4-aryl-3,4- dihydro[1,3,5]triazino[1,2-a]benzimidazoles
by: Dolzhenko, A.V., et al.
Published: (2014)

Synthesis and pharmacological characterization of a new series of 5,7-disubstituted-[1,2,4]triazolo[1,5-a][1,3,5]triazine derivatives as adenosine receptor antagonists: A preliminary inspection of ligand-receptor recognition process
by: Pastorin, G., et al.
Published: (2014)

Antiproliferative activity against MCF-7 breast cancer cells by diamino-triazaspirodiene antifolates
by: Ma, X., et al.
Published: (2014)