Effects of a novel mGlu 2/3 receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid

Effects of a novel mGlu 2/3 receptor agonist prodrug, LY2140023 monohydrate, on central monoamine turnover as determined in human and rat cerebrospinal fluid

10.1007/s00213-011-2427-9

Saved in:

書目詳細資料
Main Authors:	Lowe, S., Dean, R., Ackermann, B., Jackson, K., Natanegara, F., Anderson, S., Eckstein, J., Yuen, E., Ayan-Oshodi, M., Ho, M., McKinzie, D., Perry, K., Svensson, K.
其他作者:	INSTITUTE OF MOLECULAR & CELL BIOLOGY
格式:	Article
出版:	2014
主題:	Cerebrospinal fluid CNS pharmacodynamics Dopamine Glutamate mGlu2,3 agonists Serotonin
在線閱讀:	http://scholarbank.nus.edu.sg/handle/10635/115077
標簽:	添加標簽沒有標簽, 成為第一個標記此記錄!

相似書籍

Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: Association with N-methyl-d-aspartic acid receptor up-regulation
由: Gray, L., et al.
出版: (2016)

Adverse events in healthy subjects exposed to single and multiple doses of LY2140023 monohydrate: Pooled results from 10 phase 1 studies
由: Ayan-Oshodi, M., et al.
出版: (2014)

Metabotropic glutamate receptors in the control of neuronal activity and as targets for development of anti-epileptogenic drugs
由: Tang, F.R., et al.
出版: (2014)

MGlu receptors
出版: (2020)

Metabotropic glutamate receptors as targets for novel antipsychotic treatments
由: Gray, L.J., et al.
出版: (2016)

Hydrogen transportation properties in carbon nano-scroll investigated by using molecular dynamics simulations
由: Huang, Jie, et al.
出版: (2018)

Mechanical properties of bundled carbon nanoscroll
由: Huang, Jie, et al.
出版: (2018)

Synthesis and biological evaluation of dihydropyrano-[2,3-c]pyrazoles as a new class of PPARγ partial agonists
由: Qvortrup, Katrine, et al.
出版: (2017)

Spontaneous cerebrospinal fluid rhinorrhoea: Computed tomography and magnetic resonance imaging findings
由: Choong, C.C., et al.
出版: (2016)

Pre- and/or post-synaptic localisation of metabotropic glutamate receptor 1α (mGluR1α) and 2/3 (mGluR2/3) in the rat spinal cord
由: Tang, F.R., et al.
出版: (2012)

Phase I and pharmacodynamic study of an orally administered novel inhibitor of histone deacetylases, SB939, in patients with refractory solid malignancies
由: Yong, W.P., et al.
出版: (2014)

Optimizing dihydroartemisinin-piperaquine dose regimens in a paediatric population: a pharmacokinetic-pharmacodynamic approach using monte-carlo simulations
由: Palang Chotsiri, et al.
出版: (2015)

Inhaled β2-adrenergic agonists in asthma: The evolving dilemma
由: Hui, K.P.
出版: (2016)

Cerebrospinal fluid cytokines in metastatic group 3 and 4 medulloblastoma
由: Low, Sharon YY, et al.
出版: (2023)

Localisation of Ionotropic Glutamate Receptor Subunits, and γ-Aminobutyric Acid (GABA) in the Monkey Amygdala - A Double Immunolabelling and Electron Microscopic Study
由: He, Y., et al.
出版: (2012)

Positron emission tomographic imaging in drug discovery
由: Ghosh, Krishna Kanta, et al.
出版: (2022)

Poster: Modelling the tumor shrinkage pharmacodynamics with BlenX
由: Lecca, P., et al.
出版: (2014)

In vivo detection of venous sinus distension due to intracranial hypotension in small animal using pulsed-laser-diode photoacoustic tomography
由: Rajendran, Praveenbalaji, et al.
出版: (2021)

Resveratrol for cancer therapy: Challenges and future perspectives
由: Ren, Boxu, et al.
出版: (2022)

Reissner fibre-induced urotensin signalling from cerebrospinal fluid-contacting neurons prevents scoliosis of the vertebrate spine
由: Lu, H., et al.
出版: (2021)

Unintended changes in cognition, mood, and behavior arising from cell-based interventions for neurological conditions: Ethical challenges
由: Duggan, P.S., et al.
出版: (2016)

Distribution of glutamate receptor subunit GluR1 and GABA in human cerebral neocortex: A double immunolabelling and electron microscopic study
由: He, Y., et al.
出版: (2012)

A new treatment of menorrhagia using GnRH-agonist cyclically without prolonged down-regulation and loss of bone density: A case study
由: Chan, C.L.K., et al.
出版: (2013)

Effects of adenosine receptor agonists on nitric oxide release in mouse during endotoxemia
由: Wei, M.H., et al.
出版: (2011)

Synthetic and natural Peroxisome Proliferator-Activated Receptor (PPAR) agonists as candidates for the therapy of the metabolic syndrome
由: Tan, Chek Kun, et al.
出版: (2017)

Fluvastatin: Efficacy and safety in reducing cardiac events
由: Chan, M.Y., et al.
出版: (2016)

Clinical experience with high-dose polymyxin b against carbapenem-resistant gram-negative bacterial infections—a cohort study
由: Cai, Y., et al.
出版: (2021)

PHARMACODYNAMICS, PHARMACOKINETICS AND PHARMACOGENETICS OF DOXORUBICIN IN SINGAPOREAN BREAST CANCER PATIENTS
由: FAN LU
出版: (2011)

Expression of glutamate receptor subunit 1 and nitric oxide synthase in the hypoglossal nucleus and dorsal vagal nucleus in the rat after neurectomy
由: Jinn-Fei, Y., et al.
出版: (2015)

Exotic solutions of the conformal scalar curvature equation in ℝN
由: Leung, M.C.
出版: (2014)

Dual PPARα/γ agonist saroglitazar improves liver histopathology and biochemistry in experimental NASH models
由: Jain, Mukul R., et al.
出版: (2019)

Hydrogen sulfide: Neurochemistry and neurobiology
由: Qu, K., et al.
出版: (2011)

Species differences in the distribution of the glutamate receptor subunit, GluR1, in the rat and monkey entorhinal cortex.
由: He, Y., et al.
出版: (2016)

Molecular and pharmacodynamic properties of estrogenic extracts from the traditional Chinese medicinal herb, Epimedium
由: Yap, S.P., et al.
出版: (2011)

Effect of ubidecarenone on warfarin anticoagulation and pharmacokinetics of warfarin enantiomers in rats
由: Zhou, S., et al.
出版: (2014)

Effect of omeprazole on the anticoagulant activity and the pharmacokinetics of warfarin enantiomers in rats
由: Zhou, Q., et al.
出版: (2014)

Pharmacokinetic and pharmacodynamic studies of mycophenolic acid in renal transplant recipients
由: NWAY NWAY AYE
出版: (2010)

Effect of rutin on warfarin anticoagulation and pharmacokinetics of warfarin enantiomers in rats
由: Chan, E., et al.
出版: (2014)

On the functional overlap between two Drosophila POU homeo domain genes and the cell fate specification of a CNS neural precursor
由: Su Ling Yeo, et al.
出版: (2014)

Diagnosis of Nipah virus encephalitis by electron microscopy of cerebrospinal fluid
由: Chow, V.T.K., et al.
出版: (2012)