Scavenging Circulating Mitochondrial DNA as a Potential Therapeutic Option for Multiple Organ Dysfunction in Trauma Hemorrhage

• Main Authors: Aswani, Andrew, Manson, Joanna, Itagaki, Kiyoshi, Chiazza, Fausto, Collino, Massimo, Liao, Wupeng Winston, CHAN TZE KHEE, WONG WAI-SHIU,FRED, Hauser, Carl J, Thiemermann, Chris, Brohi, Karim
• Other Authors: DEPT OF PHARMACOLOGY
• Format: Article
• Language: English
• Published: FRONTIERS MEDIA SA 2019
• Subjects: Science & Technology; Life Sciences & Biomedicine; Immunology; trauma; mitochondrial DNA; damage-associated molecular patterns; nucleic acid scavenger; multiple organ dysfunction syndrome; trauma hemorrhage; Toll-like receptor-9; sterile inflammation; ACID-BINDING POLYMERS; OPEN-HEART-SURGERY; FORMYL PEPTIDE RECEPTORS; P38 MAP KINASE; NLRP3 INFLAMMASOME; RENAL TOXICITY; ANTIINFLAMMATORY AGENTS; HEPARIN NEUTRALIZATION; MOLECULAR-PATTERNS; CELL NECROSIS
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/158026
• Institution: National University of Singapore

10.3389/fimmu.2018.00891