GLIPR1 modulates the response of cisplatin-resistant human lung cancer cells to cisplatin

• Main Authors: Gong X., Liu J., Zhang D., Yang D., Min Z., Wen X., Wang G., Li H., Song Y., Bai C., Li J., Zhou J.
• Other Authors: BIOLOGY (NU)
• Format: Article
• Published: 2019
• Subjects: caspase 3; cisplatin; glioma pathogenesis related protein 1; messenger RNA; nicotinamide adenine dinucleotide adenosine diphosphate ribosyltransferase; protein bcl 2; tumor suppressor protein; unclassified drug; antineoplastic agent; GLIPR1 protein, human; nerve protein; small interfering RNA; tumor protein; apoptosis; Article; bright field microscopy; cancer resistance; cell counting; cell counting kit 8 assay; cell proliferation; controlled study; down regulation; enzyme inhibition; flow cytometry; human; human cell; lung adenocarcinoma; mitochondrial membrane potential; protein cleavage; protein expression; protein function; protein RNA binding; real time polymerase chain reaction; signal transduction; Western blotting; adenocarcinoma; antagonists and inhibitors; Carcinoma, Large Cell; drug effects; drug resistance; gene expression regulation; genetics; Lung Neoplasms; metabolism; pathology; tumor cell culture; Adenocarcinoma; Antineoplastic Agents; Apoptosis; Cell Proliferation; Cisplatin; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Membrane Potential, Mitochondrial; Neoplasm Proteins; Nerve Tissue Proteins; Poly(ADP-ribose) Polymerases; RNA, Small Interfering; Tumor Cells, Cultured
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161181
• Institution: National University of Singapore

10.1371/journal.pone.0182410