Actinic keratosis modelling in mice: A translational study

• Main Authors: Pillon A., Gomes B., Vandenberghe I., Cartron V., Cèbe P., Blanchet J.-C., Sibaud V., Guilbaud N., Audoly L., Lamant L., Kruczynski A.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: CD3 antigen; fluorouracil; ingenol mebutate; Ki 67 antigen; protein p53; immunosuppressive agent; acanthosis; actinic keratosis; aged; animal cell; animal experiment; animal model; animal tissue; Article; basement membrane; cancer model; clinical article; controlled study; dermatoscope; disease classification; disease course; drug efficacy; histopathology; human; human cell; human tissue; human versus animal comparison; immunohistochemistry; keratinocyte; light exposure; mouse; mouse model; nonhuman; phenotype; protein expression; reproducibility; skin carcinoma; skin defect; translational research; ultraviolet B radiation; very elderly; animal; comparative study; disease model; epiluminescence microscopy; hairless mouse; Keratosis, Actinic; pathology; ultraviolet radiation; Animals; Dermoscopy; Disease Models, Animal; Fluorouracil; Humans; Immunosuppressive Agents; Mice; Mice, Hairless; Translational Medical Research; Ultraviolet Rays
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161189
• Institution: National University of Singapore

10.1371/journal.pone.0179991