Zika virus infection modulates the metabolomic profile of microglial cells

• Main Authors: Diop F., Vial T., Ferraris P., Wichit S., Bengue M., Hamel R., Talignani L., Liegeois F., Pompon J., Yssel H., Marti G., Missé D.
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Published: 2019
• Subjects: carboxylic acid; ceramide; chemokine receptor CX3CR1; dodecanedioic acid; drug metabolite; inducible nitric oxide synthase; interleukin 1beta; interleukin 6; lysophosphatidylcholine; lysophospholipid; nitric oxide; phosphatidylcholine; phosphatidylserine; phospholipid; sebacic acid; sphingomyelin; tumor necrosis factor; unclassified drug; undecanedioic acid; animal cell; apoptosis; Article; central nervous system; controlled study; fetus; human; human cell; metabolomics; microglia; nerve cell differentiation; nerve cell plasticity; nervous system inflammation; nonhuman; protein expression; signal transduction; upregulation; virion; virus replication; Zika fever; animal; cell culture; Chlorocebus aethiops; cytology; metabolism; metabolome; microcephaly; mosquito; pathology; physiology; Vero cell line; virology; Zika virus; Animals; Cells, Cultured; Cercopithecus aethiops; Culicidae; Fetus; Humans; Metabolome; Metabolomics; Microcephaly; Microglia; Vero Cells; Virus Replication; Zika Virus; Zika Virus Infection
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161211
• Institution: National University of Singapore

10.1371/journal.pone.0206093