A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies
10.1371/journal.pone.0197101
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sg-nus-scholar.10635-1612292024-11-12T16:35:51Z A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies Tan H.-Y. Trier S. Rahbek U.L. Dufva M. Kutter J.P. Andresen T.L. BIOMED INST FOR GLOBAL HEALTH RES & TECH aminopeptidase dextran insulin mannitol multidrug resistance protein 1 politef rhodamine 123 tight junction protein ABC transporter subfamily B ABCB1 protein, human dextran insulin maltose mannitol rhodamine 123 tetradecyl maltoside Article biocompatibility biological model Caco-2 cell line cell differentiation cell growth controlled study drug transport electric resistance enzyme activity human human cell hydrophilicity immunocytochemistry intestine melting point microfluidics monolayer culture mucus permeability barrier analogs and derivatives Caco-2 cell line cytology devices drug effect intestine absorption intestine mucosa lab on a chip metabolism microfluidic analysis procedures ATP Binding Cassette Transporter, Sub-Family B Caco-2 Cells Dextrans Humans Insulin Intestinal Absorption Intestinal Mucosa Lab-On-A-Chip Devices Maltose Mannitol Microfluidic Analytical Techniques Rhodamine 123 10.1371/journal.pone.0197101 PLoS ONE 13 5 e0197101 2019-11-01T08:15:25Z 2019-11-01T08:15:25Z 2018 Article Tan H.-Y., Trier S., Rahbek U.L., Dufva M., Kutter J.P., Andresen T.L. (2018). A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies. PLoS ONE 13 (5) : e0197101. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0197101 19326203 https://scholarbank.nus.edu.sg/handle/10635/161229 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101 |
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aminopeptidase dextran insulin mannitol multidrug resistance protein 1 politef rhodamine 123 tight junction protein ABC transporter subfamily B ABCB1 protein, human dextran insulin maltose mannitol rhodamine 123 tetradecyl maltoside Article biocompatibility biological model Caco-2 cell line cell differentiation cell growth controlled study drug transport electric resistance enzyme activity human human cell hydrophilicity immunocytochemistry intestine melting point microfluidics monolayer culture mucus permeability barrier analogs and derivatives Caco-2 cell line cytology devices drug effect intestine absorption intestine mucosa lab on a chip metabolism microfluidic analysis procedures ATP Binding Cassette Transporter, Sub-Family B Caco-2 Cells Dextrans Humans Insulin Intestinal Absorption Intestinal Mucosa Lab-On-A-Chip Devices Maltose Mannitol Microfluidic Analytical Techniques Rhodamine 123 |
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aminopeptidase dextran insulin mannitol multidrug resistance protein 1 politef rhodamine 123 tight junction protein ABC transporter subfamily B ABCB1 protein, human dextran insulin maltose mannitol rhodamine 123 tetradecyl maltoside Article biocompatibility biological model Caco-2 cell line cell differentiation cell growth controlled study drug transport electric resistance enzyme activity human human cell hydrophilicity immunocytochemistry intestine melting point microfluidics monolayer culture mucus permeability barrier analogs and derivatives Caco-2 cell line cytology devices drug effect intestine absorption intestine mucosa lab on a chip metabolism microfluidic analysis procedures ATP Binding Cassette Transporter, Sub-Family B Caco-2 Cells Dextrans Humans Insulin Intestinal Absorption Intestinal Mucosa Lab-On-A-Chip Devices Maltose Mannitol Microfluidic Analytical Techniques Rhodamine 123 Tan H.-Y. Trier S. Rahbek U.L. Dufva M. Kutter J.P. Andresen T.L. A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies |
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10.1371/journal.pone.0197101 |
author2 |
BIOMED INST FOR GLOBAL HEALTH RES & TECH |
author_facet |
BIOMED INST FOR GLOBAL HEALTH RES & TECH Tan H.-Y. Trier S. Rahbek U.L. Dufva M. Kutter J.P. Andresen T.L. |
format |
Article |
author |
Tan H.-Y. Trier S. Rahbek U.L. Dufva M. Kutter J.P. Andresen T.L. |
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Tan H.-Y. |
title |
A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies |
title_short |
A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies |
title_full |
A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies |
title_fullStr |
A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies |
title_full_unstemmed |
A multi-chamber microfluidic intestinal barrier model using Caco-2 cells for drug transport studies |
title_sort |
multi-chamber microfluidic intestinal barrier model using caco-2 cells for drug transport studies |
publishDate |
2019 |
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https://scholarbank.nus.edu.sg/handle/10635/161229 |
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1821224888815321088 |