Silencing BRE Expression in Human Umbilical Cord Perivascular (HUCPV) Progenitor Cells Accelerates Osteogenic and Chondrogenic Differentiation

• Main Authors: Chen E., Tang M.K., Yao Y., Yau W.W.Y., Lo L.M., Yang X., Chui Y.L., Chan J., Lee K.K.H.
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Format: Article
• Published: 2019
• Subjects: actin binding protein; adaptor protein; bone morphogenetic protein; fibroblast growth factor; protein BRE; small interfering RNA; transforming growth factor beta; unclassified drug; animal cell; article; bone development; BRE gene; cell culture; cell differentiation; cell renewal; chondrogenesis; controlled study; down regulation; embryonic stem cell; epigenetics; Fgf5 gene; FOXO1a gene; gene; gene expression; gene silencing; human; human cell; human tissue; human umbilical cord perivascular progenitor cell; microarray analysis; multipotent stem cell; nonhuman; Oct4 gene; pluripotent stem cell; protein expression; protein protein interaction; proteomics; signal transduction; stem cell; transcription regulation; Animals; Bone Morphogenetic Proteins; Cell Differentiation; Chemokines; Chondrocytes; Chondrogenesis; Cytoskeletal Proteins; Epigenesis, Genetic; Fibroblast Growth Factors; Gene Silencing; Homeodomain Proteins; Humans; Mice; Multipotent Stem Cells; Nerve Tissue Proteins; Octamer Transcription Factor-3; Oligonucleotide Array Sequence Analysis; Osteoblasts; Osteogenesis; Proteome; Proteomics; RNA, Small Interfering; Signal Transduction; Stem Cells; Transforming Growth Factor beta; Umbilical Cord
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161286
• Institution: National University of Singapore

10.1371/journal.pone.0067896