Age and CD161 Expression Contribute to Inter-Individual Variation in Interleukin-23 Response in CD8+ Memory Human T Cells

• Main Authors: Shen H., Zhang W., Abraham C., Cho J.H.
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: 2019
• Subjects: CD161 antigen; interleukin 23; interleukin 23 receptor; retinoid related orphan receptor alpha; retinoid related orphan receptor gamma; STAT3 protein; age; antigen expression; article; CD4+ T lymphocyte; CD8+ T lymphocyte; controlled study; fluorescence activated cell sorting; gene expression; gene expression profiling; human; human cell; memory T lymphocyte; natural killer cell; protein expression; protein phosphorylation; real time polymerase chain reaction; Th17 cell; Western blotting; Adolescent; Adult; Age Factors; B-Lymphocyte Subsets; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cells, Cultured; Female; Gene Expression; Genetic Variation; Humans; Immunologic Memory; Immunophenotyping; Interleukin-23; Male; Middle Aged; NK Cell Lectin-Like Receptor Subfamily B; Nuclear Receptor Subfamily 1, Group F, Member 3; Receptors, Interleukin; Signal Transduction; STAT3 Transcription Factor; T-Lymphocyte Subsets
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161339
• Institution: National University of Singapore

10.1371/journal.pone.0057746