Suppression of Mitochondrial Electron Transport Chain Function in the Hypoxic Human Placenta: A Role for miRNA-210 and Protein Synthesis Inhibition

• Main Authors: Colleoni F., Padmanabhan N., Yung H.-W., Watson E.D., Cetin I., Tissot van Patot M.C., Burton G.J., Murray A.J.
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Format: Article
• Published: 2019
• Subjects: cytochrome c oxidase; cytochrome c oxidase assembly protein 10; iron sulfur protein; messenger RNA; microRNA 210; reduced nicotinamide adenine dinucleotide dehydrogenase (ubiquinone); unclassified drug; adult; aerobic metabolism; article; cell specificity; controlled study; disorders of mitochondrial functions; energy metabolism; female; gene expression; gene function; human; human cell; human tissue; intrauterine growth retardation; mitochondrial energy transfer; mitochondrial respiration; oxidative stress; oxygen concentration; oxygen consumption; oxygen transport; pathogenesis; placenta disorder; placental hypoxia; protein processing; protein synthesis inhibition; transcription regulation
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161346
• Institution: National University of Singapore

10.1371/journal.pone.0055194