Effects of leucine supplementation and serum withdrawal on branched-chain amino acid pathway gene and protein expression in mouse adipocytes

• Main Authors: Kitsy A., Carney S., Vivar J.C., Knight M.S., Pointer M.A., Gwathmey J.K., Ghosh S.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: 2 oxoisovalerate dehydrogenase (lipoamide); branched chain amino acid; branched chain amino acid transaminase 2; leucine; unclassified drug; culture medium; peroxisome proliferator activated receptor gamma; adipocyte; adipogenesis; amino acid metabolism; animal cell; article; BCAA gene; Bcat2 gene; BCKDHA gene; cell differentiation; controlled study; gene expression; gene expression regulation; gene induction; mouse; nonhuman; nutrient dynamics; protein expression; signal transduction; supplementation; transcriptomics; 3T3 cell line; animal; biosynthesis; genetics; metabolism; protein synthesis; 3T3-L1 Cells; Amino Acids, Branched-Chain; Animals; Biosynthetic Pathways; Cell Differentiation; Culture Media, Serum-Free; Leucine; Mice; PPAR gamma; Protein Biosynthesis
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161397
• Institution: National University of Singapore

10.1371/journal.pone.0102615