ZO-1 and ZO-2 are required for extra-embryonic endoderm integrity, primitive ectoderm survival and normal cavitation in embryoid bodies derived from mouse embryonic stem cells

• Main Authors: Phua D.C.Y., Xu J., Ali S.M., Boey A., Gounko N.V., Hunziker W.
• Other Authors: PHYSIOLOGY
• Format: Article
• Published: 2019
• Subjects: ezrin; podocalyxin; protein ZO1; protein ZO2; podocan protein, mouse; protein; Tjp1 protein, mouse; Tjp2 protein, mouse; animal cell; apical membrane; article; basement membrane; cavity formation; controlled study; ectoderm; embryo; embryo development; embryoid body; embryonic stem cell; endoderm; epithelium cell; in vitro study; microvillus; morphogenesis; mouse; nonhuman; protein expression; protein function; protein localization; survival rate; tight junction; animal; cytology; gene expression regulation; genetics; knockout mouse; metabolism; Animals; Ectoderm; Embryoid Bodies; Embryonic Stem Cells; Endoderm; Gene Expression Regulation, Developmental; Mice; Mice, Knockout; Proteins; Zonula Occludens-1 Protein; Zonula Occludens-2 Protein
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161406
• Institution: National University of Singapore

10.1371/journal.pone.0099532