The NOD-like receptor signalling pathway in Helicobacter pylori infection and related gastric cancer: A case-control study and gene expression analyses

• Main Authors: Castaño-Rodríguez N., Kaakoush N.O., Goh K.-L., Fock K.M., Mitchell H.M.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: immunoglobulin enhancer binding protein; interleukin 1beta converting enzyme; nucleotide binding oligomerization domain like receptor; cytokine; pattern recognition receptor; adult; article; BIRC3 gene; carcinogenesis; CARD8 gene; case control study; CASP1 gene; CCL5 gene; Chinese; controlled study; Cxcl1 gene; CXCL2 gene; female; gene; gene expression profiling; gene expression regulation; genetic association; genetic polymorphism; genetic risk; Helicobacter infection; Helicobacter pylori; human; IFNB1 gene; IL12B gene; IL6 gene; major clinical study; male; NFKB1 gene; NLRC4 gene; NLRC5 gene; NLRP12 gene; nlrp3 gene; NLRP9 gene; NLRX1 gene; nonhuman; PTGS2 gene; signal transduction; stomach cancer; TNF gene; aged; allele; Asian continental ancestry group; cell line; China; complication; genetic predisposition; genetics; genotype; metabolism; middle aged; risk factor; Stomach Neoplasms; very elderly; Adult; Aged; Aged, 80 and over; Alleles; Asian Continental Ancestry Group; Case-Control Studies; Cell Line; Cytokines; Female; Gene Expression Profiling; Gene Expression Regulation; Genetic Predisposition to Disease; Genotype; Helicobacter Infections; Humans; Male; Middle Aged; Polymorphism, Genetic; Receptors, Pattern Recognition; Risk Factors; Signal Transduction
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161407
• Institution: National University of Singapore

10.1371/journal.pone.0098899