Sequencing of Pax6 Loci from the Elephant Shark Reveals a Family of Pax6 Genes in Vertebrate Genomes, Forged by Ancient Duplications and Divergences

• Main Authors: Ravi V., Bhatia S., Gautier P., Loosli F., Tay B.-H., Tay A., Murdoch E., Coutinho P., van Heyningen V., Brenner S., Venkatesh B., Kleinjan D.A.
• Other Authors: MEDICINE
• Format: Article
• Published: 2019
• Subjects: transcription factor PAX6; animal cell; animal tissue; article; Callorhinchus milii; controlled study; embryo; embryo development; gene; gene duplication; gene expression; gene locus; gene sequence; genetic analysis; genetic code; genetic conservation; genetic variability; microphthalmia; morphological trait; mouse; nonhuman; nucleotide sequence; Oryzias; Pax6 gene; phenotype; pleiotropy; retina development; sequence homology; shark; species comparison; teleost; transgenics; zebra fish; Animals; Evolution, Molecular; Eye Proteins; Gene Duplication; Gene Expression Regulation; Genetic Variation; Genome; Homeodomain Proteins; Mice; Paired Box Transcription Factors; Promoter Regions, Genetic; Repressor Proteins; Retina; Sequence Analysis, DNA; Sharks; Vertebrates; Zebrafish
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161630
• Institution: National University of Singapore

10.1371/journal.pgen.1003177