New Susceptibility Loci Associated with Kidney Disease in Type 1 Diabetes

• Main Authors: Sandholm N., Salem R.M., McKnight A.J., Brennan E.P., Forsblom C., Isakova T., McKay G.J., Williams W.W., Sadlier D.M., Mäkinen V.-P., Swan E.J., Palmer C., Boright A.P., Ahlqvist E., Deshmukh H.A., Keller B.J., Huang H., Ahola A.J., Fagerholm E., Gordin D., Harjutsalo V., He B., Heikkilä O., Hietala K., Kytö J., Lahermo P., Lehto M., Lithovius R., Österholm A.-M., Parkkonen M., Pitkäniemi J., Rosengård-Bärlund M., Saraheimo M., Sarti C., Söderlund J., Soro-Paavonen A., Syreeni A., Thorn L.M., Tikkanen H., Tolonen N., Tryggvason K., Tuomilehto J., Wadén J., Gill G.V., Prior S., Guiducci C., Mirel D.B., Taylor A., Hosseini S.M., Parving H.-H., Rossing P., Tarnow L., Ladenvall C., Alhenc-Gelas F., Lefebvre P., Rigalleau V., Roussel R., Tregouet D.-A., Maestroni A., Maestroni S., Falhammar H., Gu T., Möllsten A., Cimponeriu D., Ioana M., Mota M., Mota E., Serafinceanu C., Stavarachi M., Hanson R.L., Nelson R.G., Kretzler M., Colhoun H.M., Panduru N.M., Gu H.F., Brismar K., Zerbini G., Hadjadj S., Marre M., Groop L., Lajer M., Bull S.B., Waggott D., Paterson A.D., Savage D.A., Bain S.C., Martin F., Hirschhorn J.N., Godson C., Florez J.C., Groop P.-H., Maxwell A.P., Böger C.A.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: transforming growth factor beta1; AFF3 gene; article; chromosome 15q; diabetic nephropathy; ERBB4 gene; gene; gene expression; gene locus; genetic association; genetic susceptibility; genotype; human; insulin dependent diabetes mellitus; intron; kidney failure; kidney fibrosis; kidney tubule disorder; MCTP2 gene; pathogenesis; phenotype; quantitative trait locus; RGMA gene; single nucleotide polymorphism; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Fibrosis; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Kidney Failure, Chronic; Kidney Tubules; Nuclear Proteins; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Receptor, Epidermal Growth Factor; Transforming Growth Factor beta1
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161633
• Institution: National University of Singapore

10.1371/journal.pgen.1002921