The dynamics and prognostic potential of DNA methylation changes at stem cell gene loci in women's Cancer

• Main Authors: Zhuang J., Jones A., Lee S.-H., Ng E., Fiegl H., Zikan M., Cibula D., Sargent A., Salvesen H.B., Jacobs I.J., Kitchener H.C., Teschendorff A.E., Widschwendter M.
• Other Authors: MEDICINE
• Format: Article
• Published: 2019
• Subjects: DNA; polycomb group protein; DNA binding protein; oncoprotein; repressor protein; TET1 protein, human; article; cancer invasion; carcinogenesis; carcinoma in situ; CpG island; cytology; DNA methylation; embryonic stem cell; female; gene locus; gene targeting; gynecologic cancer; human; malignant transformation; metastasis; prediction; prognosis; protein expression; adult; aged; cancer stem cell; cell transformation; gene expression regulation; genetic epigenesis; genetics; hematopoietic stem cell; metabolism; middle aged; neoplasm; promoter region; Adult; Aged; Aged, 80 and over; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Hematopoietic Stem Cells; Humans; Middle Aged; Neoplasms; Neoplastic Stem Cells; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins; Repressor Proteins
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161644
• Institution: National University of Singapore

10.1371/journal.pgen.1002517