Positional cloning of "Lisch-like", a candidate modifier of susceptibility to type 2 diabetes in mice

• Main Authors: Dokmanovic-Chouinard M., Chung W.K., Chevre J.-C., Watson E., Yonan J., Wiegand B., Bromberg Y., Wakae N., Wright C.V., Overton J., Ghosh S., Sathe G.M., Ammala C.E., Brown K.K., Ito R., LeDuc C., Solomon K., Fischer S.G., Leibel R.L.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: glucose; hemoglobin A1c; immunoglobulin; protein 14 3 3; cell surface receptor; insulin; isoprotein; lisch like protein, mouse; lisch-like protein, mouse; animal cell; animal experiment; animal model; animal tissue; article; C57BL 6 mouse; cell division; chromosome 1q; congenic strain; controlled study; DBA 2 mouse; embryo; gene expression; genetic susceptibility; molecular cloning; mouse; non insulin dependent diabetes mellitus; nonhuman; nucleotide sequence; null allele; orthology; pancreas islet; pancreas islet beta cell; protein domain; quantitative trait locus; sequence analysis; zebra fish; amino acid sequence; animal; blood; C57BL mouse; chemistry; chromosome; cross breeding; DBA mouse; experimental diabetes mellitus; genetic predisposition; genetics; glucose blood level; glucose tolerance test; haplotype; homozygote; male; methodology; molecular genetics; mouse mutant; mutation; Danio rerio; Mus; Amino Acid Sequence; Animals; Base Sequence; Blood Glucose; Chromosomes, Mammalian; Cloning, Molecular; Crosses, Genetic; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Glucose Tolerance Test; Haplotypes; Homozygote; Insulin; Male; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Obese; Molecular Sequence Data; Mutation; Protein Isoforms; Quantitative Trait Loci; Receptors, Cell Surface
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161686
• Institution: National University of Singapore

10.1371/journal.pgen.1000137