Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans

• Main Authors: Bishop T., Lau K.W., Epstein A.C.R., Kim S.K., Jiang M., O'Rourke D., Pugh C.W., Gleadle J.M., Taylor M.S., Hodgkin J., Ratcliffe P.J.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: Caenorhabditis elegans protein; von Hippel Lindau protein; Egl 9 protein, C elegans; Egl-9 protein, C elegans; ribonuclease; article; Caenorhabditis elegans; controlled study; enzyme activity; extracellular matrix; gene expression; genetic analysis; genetic conservation; genetic similarity; genetic variability; genome analysis; genomics; microbial genetics; nonhuman; protein expression; protein function; regulatory mechanism; signal transduction; transcription regulation; animal; biological model; biology; chromosome map; cluster analysis; DNA microarray; down regulation; gene expression regulation; genome; human; metabolism; methodology; molecular evolution; molecular genetics; mutation; nucleotide sequence; time; upregulation; Caenorhabditis; Animals; Base Sequence; Caenorhabditis elegans Proteins; Chromosome Mapping; Cluster Analysis; Computational Biology; Down-Regulation; Evolution, Molecular; Extracellular Matrix; Gene Expression Regulation; Genome; Humans; Models, Genetic; Molecular Sequence Data; Mutation; Oligonucleotide Array Sequence Analysis; Ribonucleases; Time Factors; Up-Regulation; Von Hippel-Lindau Tumor Suppressor Protein
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161691
• Institution: National University of Singapore

10.1371/journal.pbio.0020289