BMP Signaling in astrocytes downregulates EGFR to modulate survival and maturation

• Main Authors: Scholze A.R., Foo L.C., Mulinyawe S., Barres B.A.
• Other Authors: ANATOMY
• Format: Article
• Published: 2019
• Subjects: aquaporin 4; bone morphogenetic protein; bone morphogenetic protein 5; epidermal growth factor receptor; fibroblast growth factor; glial fibrillary acidic protein; protein S100B; Smad1 protein; Smad5 protein; Smad8 protein; somatomedin B; Wnt7a protein; Egfr protein, rat; animal cell; animal tissue; Article; astrocyte; cell differentiation; cell heterogeneity; cell lineage; cell maturation; cell proliferation; cell survival; controlled study; down regulation; immunoblotting; immunoreactivity; in vitro study; nonhuman; oligodendroglia; prospective study; protein analysis; protein expression; protein phosphorylation; purification; rat; signal transduction; upregulation; animal; biosynthesis; gene expression regulation; genetics; metabolism; mouse; phosphorylation; physiology; Animals; Astrocytes; Bone Morphogenetic Proteins; Gene Expression Regulation, Developmental; Mice; Phosphorylation; Rats; Receptor, Epidermal Growth Factor; Signal Transduction
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161767
• Institution: National University of Singapore

10.1371/journal.pone.0110668