Biocompatibility and biodegradation studies of subconjunctival implants in rabbit eyes

• Main Authors: Peng Y., Ang M., Foo S., Lee W.S., Ma Z., Venkatraman S.S., Wong T.T.
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Published: 2019
• Subjects: biopolymer; dexamethasone plus tobramycin; polycaprolactone; polyglactin; drug carrier; lactic acid; lactide caprolactone copolymer; lactide-caprolactone copolymer; polyester; polyglycolic acid; polylactic acid polyglycolic acid copolymer; polylactic acid-polyglycolic acid copolymer; water; animal experiment; animal tissue; anterior eye segment; article; biocompatibility; biodegradation; chemosis; conjunctiva; conjunctival hyperemia; controlled study; drug delivery system; enucleation; feasibility study; histopathology; immunofluorescence; immunohistochemistry; implant; in vitro study; in vivo study; inflammation; microfilm; molecular weight; nonhuman; optical coherence tomography; rabbit; slit lamp; subconjunctival implant; vascularization; viscosity; water absorption; weight reduction; absorption; animal; chemistry; cytology; drug effect; materials testing; metabolism; prostheses and orthoses; Oryctolagus cuniculus; Absorption; Animals; Conjunctiva; Drug Carriers; Feasibility Studies; Lactic Acid; Materials Testing; Molecular Weight; Polyesters; Polyglycolic Acid; Prostheses and Implants; Rabbits; Water
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161792
• Institution: National University of Singapore

10.1371/journal.pone.0022507