Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells

10.1371/journal.pone.0015441

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Main Authors:	Wang M., Bai J., Chen W.N., Ching C.B.
Other Authors:	CHEMICAL & BIOMOLECULAR ENGINEERING
Format:	Article
Published:	2019
Subjects:	calcium ion carvedilol inositol myristic acid palmitic acid pyroglutamic acid serine threonine alanine beta adrenergic receptor blocking agent calcium carbazole derivative propanolamine derivative article calcium cell level cell line cell metabolism controlled study drug effect in vitro study mass fragmentography metabolite metabolomics smooth muscle fiber vascular smooth muscle animal chemistry cytology intracellular space metabolism metabolome methodology principal component analysis rat stereoisomerism Adrenergic beta-Antagonists Alanine Animals Calcium Carbazoles Cell Line Gas Chromatography-Mass Spectrometry Intracellular Space Metabolome Metabolomics Muscle, Smooth, Vascular Myocytes, Smooth Muscle Principal Component Analysis Propanolamines Rats Stereoisomerism
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161798
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1617982024-03-26T08:55:28Z Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells Wang M. Bai J. Chen W.N. Ching C.B. CHEMICAL & BIOMOLECULAR ENGINEERING TEMASEK LABORATORIES calcium ion carvedilol inositol myristic acid palmitic acid pyroglutamic acid serine threonine alanine beta adrenergic receptor blocking agent calcium carbazole derivative carvedilol propanolamine derivative article calcium cell level cell line cell metabolism controlled study drug effect in vitro study mass fragmentography metabolite metabolomics smooth muscle fiber vascular smooth muscle animal chemistry cytology intracellular space metabolism metabolome methodology principal component analysis rat smooth muscle fiber stereoisomerism Adrenergic beta-Antagonists Alanine Animals Calcium Carbazoles Cell Line Gas Chromatography-Mass Spectrometry Intracellular Space Metabolome Metabolomics Muscle, Smooth, Vascular Myocytes, Smooth Muscle Principal Component Analysis Propanolamines Rats Stereoisomerism 10.1371/journal.pone.0015441 PLoS ONE 5 11 e15441 2019-11-07T07:59:06Z 2019-11-07T07:59:06Z 2010 Article Wang M., Bai J., Chen W.N., Ching C.B. (2010). Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells. PLoS ONE 5 (11) : e15441. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pone.0015441 19326203 https://scholarbank.nus.edu.sg/handle/10635/161798 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	calcium ion carvedilol inositol myristic acid palmitic acid pyroglutamic acid serine threonine alanine beta adrenergic receptor blocking agent calcium carbazole derivative carvedilol propanolamine derivative article calcium cell level cell line cell metabolism controlled study drug effect in vitro study mass fragmentography metabolite metabolomics smooth muscle fiber vascular smooth muscle animal chemistry cytology intracellular space metabolism metabolome methodology principal component analysis rat smooth muscle fiber stereoisomerism Adrenergic beta-Antagonists Alanine Animals Calcium Carbazoles Cell Line Gas Chromatography-Mass Spectrometry Intracellular Space Metabolome Metabolomics Muscle, Smooth, Vascular Myocytes, Smooth Muscle Principal Component Analysis Propanolamines Rats Stereoisomerism
spellingShingle	calcium ion carvedilol inositol myristic acid palmitic acid pyroglutamic acid serine threonine alanine beta adrenergic receptor blocking agent calcium carbazole derivative carvedilol propanolamine derivative article calcium cell level cell line cell metabolism controlled study drug effect in vitro study mass fragmentography metabolite metabolomics smooth muscle fiber vascular smooth muscle animal chemistry cytology intracellular space metabolism metabolome methodology principal component analysis rat smooth muscle fiber stereoisomerism Adrenergic beta-Antagonists Alanine Animals Calcium Carbazoles Cell Line Gas Chromatography-Mass Spectrometry Intracellular Space Metabolome Metabolomics Muscle, Smooth, Vascular Myocytes, Smooth Muscle Principal Component Analysis Propanolamines Rats Stereoisomerism Wang M. Bai J. Chen W.N. Ching C.B. Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells
description	10.1371/journal.pone.0015441
author2	CHEMICAL & BIOMOLECULAR ENGINEERING
author_facet	CHEMICAL & BIOMOLECULAR ENGINEERING Wang M. Bai J. Chen W.N. Ching C.B.
format	Article
author	Wang M. Bai J. Chen W.N. Ching C.B.
author_sort	Wang M.
title	Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells
title_short	Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells
title_full	Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells
title_fullStr	Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells
title_full_unstemmed	Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells
title_sort	metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161798
_version_	1795300779957944320

Metabolomic profiling of cellular responses to carvedilol enantiomers in vascular smooth muscle cells

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