Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking

• Main Authors: Sobo K., Le Blanc I., Luyet P.-P., Fivaz M., Ferguson C., Parton R.G., Gruenberg J., Van der Goot F.G.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: 3beta (2 diethylaminoethoxy)androst 5 en 17 one; anthrax toxin; cholesterol; phospholipid; animal cell; article; cell compartmentalization; cell strain BHK; cell vacuole; CHO cell; controlled study; endosome; lysosome; membrane structure; Niemann Pick disease; nonhuman; phenotype; Vesicular stomatitis virus; animal; Cricetulus; hamster; metabolism; protein transport; Animals; Cell Compartmentation; CHO Cells; Cholesterol; Cricetinae; Endosomes; Phospholipids; Protein Transport
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161866
• Institution: National University of Singapore

10.1371/journal.pone.0000851