Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study

10.1371/journal.pgen.1007079

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Main Authors: Davis J.P., Huyghe J.R., Locke A.E., Jackson A.U., Sim X., Stringham H.M., Teslovich T.M., Welch R.P., Fuchsberger C., Narisu N., Chines P.S., Kangas A.J., Soininen P., Ala-Korpela M., Kuusisto J., Laakso M., Boehnke M., Mohlke K.L.
Other Authors: DEAN'S OFFICE (SSH SCH OF PUBLIC HEALTH)
Format: Article
Published: 2019
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Online Access:https://scholarbank.nus.edu.sg/handle/10635/161889
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spelling sg-nus-scholar.10635-1618892023-10-31T08:31:52Z Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study Davis J.P. Huyghe J.R. Locke A.E. Jackson A.U. Sim X. Stringham H.M. Teslovich T.M. Welch R.P. Fuchsberger C. Narisu N. Chines P.S. Kangas A.J. Soininen P. Ala-Korpela M. Kuusisto J. Laakso M. Boehnke M. Mohlke K.L. DEAN'S OFFICE (SSH SCH OF PUBLIC HEALTH) LIFE SCIENCES INSTITUTE SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH high density lipoprotein cholesterol low density lipoprotein cholesterol triacylglycerol high density lipoprotein cholesterol lipid lipoprotein triacylglycerol ADAMTS3 gene adult Article controlled study Finn (citizen) gene gene frequency gene locus gene sequence genetic variability genome-wide association study genotype HIF3A gene human informed consent LCAT gene limit of quantitation LIPC gene LIPG gene male PLTP gene single nucleotide polymorphism smoking Caucasian exome Finland gene frequency genetics lipid metabolism middle aged principal component analysis procedures Cholesterol, HDL European Continental Ancestry Group Exome Finland Gene Frequency Genome-Wide Association Study Genotype Humans Lipid Metabolism Lipids Lipoproteins Male Middle Aged Polymorphism, Single Nucleotide Principal Component Analysis Triglycerides 10.1371/journal.pgen.1007079 PLoS Genetics 13 10 e1007079 2019-11-08T06:43:28Z 2019-11-08T06:43:28Z 2017 Article Davis J.P., Huyghe J.R., Locke A.E., Jackson A.U., Sim X., Stringham H.M., Teslovich T.M., Welch R.P., Fuchsberger C., Narisu N., Chines P.S., Kangas A.J., Soininen P., Ala-Korpela M., Kuusisto J., Laakso M., Boehnke M., Mohlke K.L. (2017). Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study. PLoS Genetics 13 (10) : e1007079. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pgen.1007079 15537390 https://scholarbank.nus.edu.sg/handle/10635/161889 CC0 1.0 Universal http://creativecommons.org/publicdomain/zero/1.0/ Unpaywall 20191101
institution National University of Singapore
building NUS Library
continent Asia
country Singapore
Singapore
content_provider NUS Library
collection ScholarBank@NUS
topic high density lipoprotein cholesterol
low density lipoprotein cholesterol
triacylglycerol
high density lipoprotein cholesterol
lipid
lipoprotein
triacylglycerol
ADAMTS3 gene
adult
Article
controlled study
Finn (citizen)
gene
gene frequency
gene locus
gene sequence
genetic variability
genome-wide association study
genotype
HIF3A gene
human
informed consent
LCAT gene
limit of quantitation
LIPC gene
LIPG gene
male
PLTP gene
single nucleotide polymorphism
smoking
Caucasian
exome
Finland
gene frequency
genetics
lipid metabolism
middle aged
principal component analysis
procedures
Cholesterol, HDL
European Continental Ancestry Group
Exome
Finland
Gene Frequency
Genome-Wide Association Study
Genotype
Humans
Lipid Metabolism
Lipids
Lipoproteins
Male
Middle Aged
Polymorphism, Single Nucleotide
Principal Component Analysis
Triglycerides
spellingShingle high density lipoprotein cholesterol
low density lipoprotein cholesterol
triacylglycerol
high density lipoprotein cholesterol
lipid
lipoprotein
triacylglycerol
ADAMTS3 gene
adult
Article
controlled study
Finn (citizen)
gene
gene frequency
gene locus
gene sequence
genetic variability
genome-wide association study
genotype
HIF3A gene
human
informed consent
LCAT gene
limit of quantitation
LIPC gene
LIPG gene
male
PLTP gene
single nucleotide polymorphism
smoking
Caucasian
exome
Finland
gene frequency
genetics
lipid metabolism
middle aged
principal component analysis
procedures
Cholesterol, HDL
European Continental Ancestry Group
Exome
Finland
Gene Frequency
Genome-Wide Association Study
Genotype
Humans
Lipid Metabolism
Lipids
Lipoproteins
Male
Middle Aged
Polymorphism, Single Nucleotide
Principal Component Analysis
Triglycerides
Davis J.P.
Huyghe J.R.
Locke A.E.
Jackson A.U.
Sim X.
Stringham H.M.
Teslovich T.M.
Welch R.P.
Fuchsberger C.
Narisu N.
Chines P.S.
Kangas A.J.
Soininen P.
Ala-Korpela M.
Kuusisto J.
Laakso M.
Boehnke M.
Mohlke K.L.
Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study
description 10.1371/journal.pgen.1007079
author2 DEAN'S OFFICE (SSH SCH OF PUBLIC HEALTH)
author_facet DEAN'S OFFICE (SSH SCH OF PUBLIC HEALTH)
Davis J.P.
Huyghe J.R.
Locke A.E.
Jackson A.U.
Sim X.
Stringham H.M.
Teslovich T.M.
Welch R.P.
Fuchsberger C.
Narisu N.
Chines P.S.
Kangas A.J.
Soininen P.
Ala-Korpela M.
Kuusisto J.
Laakso M.
Boehnke M.
Mohlke K.L.
format Article
author Davis J.P.
Huyghe J.R.
Locke A.E.
Jackson A.U.
Sim X.
Stringham H.M.
Teslovich T.M.
Welch R.P.
Fuchsberger C.
Narisu N.
Chines P.S.
Kangas A.J.
Soininen P.
Ala-Korpela M.
Kuusisto J.
Laakso M.
Boehnke M.
Mohlke K.L.
author_sort Davis J.P.
title Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study
title_short Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study
title_full Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study
title_fullStr Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study
title_full_unstemmed Common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in Finnish men from the METSIM study
title_sort common, low-frequency, and rare genetic variants associated with lipoprotein subclasses and triglyceride measures in finnish men from the metsim study
publishDate 2019
url https://scholarbank.nus.edu.sg/handle/10635/161889
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