APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts

• Main Authors: Qian J., Wolters F.J., Beiser A., Haan M., Ikram M.A., Karlawish J., Langbaum J.B., Neuhaus J.M., Reiman E.M., Roberts J.S., Seshadri S., Tariot P.N., Woods B.M., Betensky R.A., Blacker D.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: apolipoprotein E; ApoE protein, human; aged; Alzheimer disease; APOE gene; Article; clinical trial (topic); cohort analysis; computer model; dementia; female; genetic association study; genetic counseling; genetic risk; genome-wide association study; human; major clinical study; male; mild cognitive impairment; multicenter study; prevention study; telephone interview; Cognitive Dysfunction; gene frequency; genetics; genotype; metabolism; middle aged; Netherlands; risk factor; United States; Aged; Apolipoproteins E; Cohort Studies; Dementia; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Risk Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161896
• Institution: National University of Singapore

10.1371/journal.pmed.1002254