Comparative Transcriptomic and Epigenomic Analyses Reveal New Regulators of Murine Brown Adipogenesis

• Main Authors: Brunmeir R., Wu J., Peng X., Kim S.-Y., Julien S.G., Zhang Q., Xie W., Xu F.
• Other Authors: CANCER SCIENCE INSTITUTE OF SINGAPORE
• Format: Article
• Published: 2019
• Subjects: CCAAT enhancer binding protein alpha; CCAAT enhancer binding protein beta; histone H3; long untranslated RNA; microRNA; mitogen activated protein kinase p38; protein EBF2; protein kinase Pim 1; protein RREB1; transcription factor; transcription factor Six1; transcription factor SOX13; transcriptome; unclassified drug; autoantigen; basic helix loop helix transcription factor; CCAAT enhancer binding protein; CEBPA protein, mouse; Cebpb protein, mouse; DNA binding protein; Ebf2 protein, mouse; homeodomain protein; Rreb1 protein, mouse; Six1 protein, mouse; Sox13 protein, mouse; adipogenesis; animal cell; Article; brown adipocyte; cell differentiation; cell fate; cell lineage; controlled study; embryo; enhancer region; epigenetics; gene expression; genetic transcription; human; human cell; in vitro study; mesenchymal stem cell; mouse; nonhuman; proadipocyte; protein protein interaction; transcriptomics; white adipocyte; animal; biosynthesis; brown adipose tissue; energy metabolism; gene expression regulation; genetics; growth, development and aging; mesenchymal stroma cell; metabolism; obesity; pathology; Adipogenesis; Adipose Tissue, Brown; Animals; Autoantigens; Basic Helix-Loop-Helix Transcription Factors; CCAAT-Enhancer-Binding Protein-beta; CCAAT-Enhancer-Binding Proteins; Cell Differentiation; Cell Lineage; DNA-Binding Proteins; Energy Metabolism; Gene Expression Regulation, Developmental; Homeodomain Proteins; Mesenchymal Stromal Cells; Mice; Obesity; RNA, Long Noncoding; Transcription Factors; Transcriptome
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161902
• Institution: National University of Singapore

10.1371/journal.pgen.1006474