Insight into Genotype-Phenotype Associations through eQTL Mapping in Multiple Cell Types in Health and Immune-Mediated Disease

• Main Authors: Peters J.E., Lyons P.A., Lee J.C., Richard A.C., Fortune M.D., Newcombe P.J., Richardson S., Smith K.G.C.
• Other Authors: MEDICINE
• Format: Article
• Published: 2019
• Subjects: genomic DNA; adult; ANCA associated vasculitis; Article; B lymphocyte; CD4+ T lymphocyte; CD8+ T lymphocyte; controlled study; Crohn disease; gene expression; genetic association; genetic variability; genotype; genotype phenotype correlation; human; human cell; immunocompetent cell; immunopathology; major clinical study; monocyte; neutrophil; quantitative trait locus mapping; ulcerative colitis; female; gene expression regulation; genetic association study; genetic predisposition; genetics; genome-wide association study; immunology; inflammatory bowel disease; male; metabolism; pathology; phenotype; quantitative trait locus; T lymphocyte; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Female; Gene Expression Regulation; Genetic Association Studies; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Inflammatory Bowel Diseases; Male; Monocytes; Neutrophils; Phenotype; Quantitative Trait Loci; T-Lymphocytes
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161919
• Institution: National University of Singapore

10.1371/journal.pgen.1005908