Tracking Dengue Virus Intra-host Genetic Diversity during Human-to-Mosquito Transmission

• Main Authors: Sim S., Aw P.P.K., Wilm A., Teoh G., Hue K.D.T., Nguyen N.M., Nagarajan N., Simmons C.P., Hibberd M.L.
• Other Authors: MEDICINE
• Format: Article
• Published: 2019
• Subjects: abdomen; Aedes aegypti; Article; dengue; Dengue virus; Dengue virus 2; gene mapping; gene sequence; genetic variability; haplotype; human; next generation sequencing; nonhuman; polymerase chain reaction; population size; salivary gland; single nucleotide polymorphism; virus replication; virus transmission; adult; Aedes; animal; classification; female; gastrointestinal tract; genetic selection; genetic variation; genetics; high throughput sequencing; isolation and purification; male; virology; young adult; NS1 protein, Dengue virus type 2; viral protein; virus RNA; Adult; Animals; Dengue; Dengue Virus; Female; Gastrointestinal Tract; Genetic Variation; High-Throughput Nucleotide Sequencing; Humans; Male; Polymorphism, Single Nucleotide; RNA, Viral; Salivary Glands; Selection, Genetic; Viral Nonstructural Proteins; Young Adult
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161929

10.1371/journal.pntd.0004052