The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain

10.1371/journal.pcbi.1004560

Saved in:

Bibliographic Details
Main Authors:	Huber R.G., Fan H., Bond P.J.
Other Authors:	BIOLOGY
Format:	Article
Published:	2019
Subjects:	separase phosphotransferase protein binding protein kinase ZAP 70 amino terminal sequence Article carboxy terminal sequence consensus sequence controlled study enzyme specificity enzyme structure enzyme substrate complex mathematical model protein domain protein secondary structure sequence alignment sequence analysis sequence homology structural bioinformatics binding site chemical model chemistry enzyme activation enzyme stability molecular dynamics protein conformation protein tertiary structure structure activity relation ultrastructure Binding Sites Enzyme Activation Enzyme Stability Models, Chemical Molecular Dynamics Simulation Phosphotransferases Protein Binding Protein Conformation Protein Structure, Tertiary Structure-Activity Relationship Substrate Specificity ZAP-70 Protein-Tyrosine Kinase
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161932
Tags:	Add Tag No Tags, Be the first to tag this record!
Institution:	National University of Singapore

id	sg-nus-scholar.10635-161932
record_format	dspace
spelling	sg-nus-scholar.10635-1619322024-11-09T12:44:47Z The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain Huber R.G. Fan H. Bond P.J. BIOLOGY BIOLOGICAL SCIENCES separase phosphotransferase protein binding protein kinase ZAP 70 amino terminal sequence Article carboxy terminal sequence consensus sequence controlled study enzyme specificity enzyme structure enzyme substrate complex mathematical model protein domain protein secondary structure sequence alignment sequence analysis sequence homology structural bioinformatics binding site chemical model chemistry enzyme activation enzyme stability molecular dynamics protein conformation protein tertiary structure structure activity relation ultrastructure Binding Sites Enzyme Activation Enzyme Stability Models, Chemical Molecular Dynamics Simulation Phosphotransferases Protein Binding Protein Conformation Protein Structure, Tertiary Structure-Activity Relationship Substrate Specificity ZAP-70 Protein-Tyrosine Kinase 10.1371/journal.pcbi.1004560 PLoS Computational Biology 11 10 e1004560 2019-11-08T08:47:02Z 2019-11-08T08:47:02Z 2015 Article Huber R.G., Fan H., Bond P.J. (2015). The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain. PLoS Computational Biology 11 (10) : e1004560. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pcbi.1004560 1553734X https://scholarbank.nus.edu.sg/handle/10635/161932 Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	separase phosphotransferase protein binding protein kinase ZAP 70 amino terminal sequence Article carboxy terminal sequence consensus sequence controlled study enzyme specificity enzyme structure enzyme substrate complex mathematical model protein domain protein secondary structure sequence alignment sequence analysis sequence homology structural bioinformatics binding site chemical model chemistry enzyme activation enzyme stability molecular dynamics protein conformation protein tertiary structure structure activity relation ultrastructure Binding Sites Enzyme Activation Enzyme Stability Models, Chemical Molecular Dynamics Simulation Phosphotransferases Protein Binding Protein Conformation Protein Structure, Tertiary Structure-Activity Relationship Substrate Specificity ZAP-70 Protein-Tyrosine Kinase
spellingShingle	separase phosphotransferase protein binding protein kinase ZAP 70 amino terminal sequence Article carboxy terminal sequence consensus sequence controlled study enzyme specificity enzyme structure enzyme substrate complex mathematical model protein domain protein secondary structure sequence alignment sequence analysis sequence homology structural bioinformatics binding site chemical model chemistry enzyme activation enzyme stability molecular dynamics protein conformation protein tertiary structure structure activity relation ultrastructure Binding Sites Enzyme Activation Enzyme Stability Models, Chemical Molecular Dynamics Simulation Phosphotransferases Protein Binding Protein Conformation Protein Structure, Tertiary Structure-Activity Relationship Substrate Specificity ZAP-70 Protein-Tyrosine Kinase Huber R.G. Fan H. Bond P.J. The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain
description	10.1371/journal.pcbi.1004560
author2	BIOLOGY
author_facet	BIOLOGY Huber R.G. Fan H. Bond P.J.
format	Article
author	Huber R.G. Fan H. Bond P.J.
author_sort	Huber R.G.
title	The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain
title_short	The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain
title_full	The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain
title_fullStr	The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain
title_full_unstemmed	The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain
title_sort	structural basis for activation and inhibition of zap-70 kinase domain
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161932
_version_	1821192004476862464

The Structural Basis for Activation and Inhibition of ZAP-70 Kinase Domain

Similar Items