A high-density genome-wide association screen of sporadic als in US veterans

• Main Authors: Kwee L.C., Liu Y., Haynes C., Gibson J.R., Stone A., Schichman S.A., Kamel F., Nelson L.M., Topol B., van Den Eeden S.K., Tanner C.M., Cudkowicz M.E., Grasso D.L., Lawson R., Muralidhar S., Oddone E.Z., Schmidt S., Hauser M.A.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: 2019
• Subjects: adult; amyotrophic lateral sclerosis; article; CACNA2D3 gene; case control study; Caucasian; CCDC93 gene; CDH8 gene; controlled study; CTSC gene; DPP6 gene; ELF3 gene; EN1 gene; female; GCNT4 gene; gene; gene location; gene replication; genetic association; genetic heterogeneity; genetic identification; genotype; heredity; human; incidence; INSIG2 gene; ITPR2 gene; KIFAP3 gene; LOC100506746 gene; LOC285419 gene; LOC647946 gene; MACROD2 gene; major clinical study; male; NUFIP1 gene; NUFIPI gene; outcome assessment; PARK2 gene; pathogenesis; PCSK2 gene; phenotype; RGS6 gene; SETBP1 gene; single nucleotide polymorphism; survival time; UNC13A gene; UNC13C gene; United States; veteran; ZNF704 gene; ZNRF3 gene; aged; follow up; genetics; human genome; middle aged; mortality; proportional hazards model; survival; dipeptidyl peptidase; DPP6 protein, human; nerve protein; potassium channel; Aged; Amyotrophic Lateral Sclerosis; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; European Continental Ancestry Group; Female; Follow-Up Studies; Genome, Human; Genome-Wide Association Study; Genotype; Humans; Male; Middle Aged; Nerve Tissue Proteins; Phenotype; Polymorphism, Single Nucleotide; Potassium Channels; Proportional Hazards Models; Survival Analysis; Veterans
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161992
• Institution: National University of Singapore

10.1371/journal.pone.0032768