The mechanical behavior of mutant K14-R125P keratin bundles and networks in NEB-1 keratinocytes

• Main Authors: Beriault D.R., Haddad O., McCuaig J.V., Robinson Z.J., Russell D., Lane E.B., Fudge D.S.
• Other Authors: PATHOLOGY
• Format: Article
• Published: 2019
• Subjects: F actin; K14 protein; keratin; latrunculin A; unclassified drug; actin; cytokeratin 14; green fluorescent protein; hybrid protein; KRT14 protein, human; mutant protein; article; cell structure; cell survival; cell viability; controlled study; cytoskeleton; epidermolysis bullosa simplex; human; human cell; keratinocyte; mechanical stress; microtubule; osmotic stress; protein assembly; protein expression; Western blotting; amino acid substitution; biomechanics; cell line; chemistry; fluorescence microscopy; genetics; metabolism; osmotic pressure; pathology; protein quaternary structure; Actins; Amino Acid Substitution; Biomechanics; Blotting, Western; Cell Line; Cell Survival; Cytoskeleton; Epidermolysis Bullosa Simplex; Green Fluorescent Proteins; Humans; Keratin-14; Keratinocytes; Microscopy, Fluorescence; Microtubules; Mutant Proteins; Osmotic Pressure; Protein Structure, Quaternary; Recombinant Fusion Proteins; Stress, Mechanical
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/161999
• Institution: National University of Singapore

10.1371/journal.pone.0031320