BCG induces protection against Mycobacterium tuberculosis infection in the wistar rat model

• Main Authors: Singhal A., Mathys V., Kiass M., Creusy C., Delaire B., Aliouat E.M., Dartois V., Kaplan G., Bifani P.
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: 2019
• Subjects: BCG vaccine; CD4 antigen; CD8 antigen; alpha interferon; beta interferon; interleukin 4; animal cell; animal experiment; animal model; animal tissue; article; BCG vaccination; CD8+ T lymphocyte; cell count; controlled study; drug efficacy; gene expression; gene function; granulomatosis; histopathology; immune response; immunohistochemistry; lung granuloma; Mycobacterium tuberculosis; nonhuman; pneumonia; rat; regulatory mechanism; Th1 cell; Th2 cell; treatment response; tuberculosis; animal; CD4+ T lymphocyte; cluster analysis; cytology; disease model; female; granuloma; immunology; inflammation; lung; metabolism; methodology; pathology; Wistar rat; Animals; BCG Vaccine; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cluster Analysis; Disease Models, Animal; Female; Granuloma; Immunohistochemistry; Inflammation; Interferon-alpha; Interferon-beta; Interleukin-4; Lung; Rats; Rats, Wistar; Th1 Cells; Tuberculosis
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/162020
• Institution: National University of Singapore

10.1371/journal.pone.0028082