Gene transfer using micellar nanovectors inhibits choroidal neovascularization in vivo

• Main Authors: Iriyama A., Oba M., Ishii T., Nishiyama N., Kataoka K., Tamaki Y., Yanagi Y.
• Other Authors: DEAN'S OFFICE (DUKE-NUS MEDICAL SCHOOL)
• Format: Article
• Published: 2019
• Subjects: alanine aminotransferase; aspartate aminotransferase; creatinine; urea; vasculotropin receptor 1; yellow fluorescent protein; bacterial protein; DNA; fluorescein; photoprotein; polymer; yellow fluorescent protein, Bacteria; animal experiment; animal model; article; controlled study; fluorescence microscopy; gene expression; gene transfer; histopathology; immunohistochemistry; in vivo study; laser coagulation; male; micelle; mouse; nonhuman; pigment epithelium; plasmid; protein expression; quantitative analysis; retina fluorescein angiography; retina macula age related degeneration; signal transduction; subretinal neovascularization; urea nitrogen blood level; Western blotting; animal; C57BL mouse; chemistry; disease course; disease model; gene vector; metabolism; methodology; pathology; retina macula degeneration; Animals; Bacterial Proteins; Choroidal Neovascularization; Disease Models, Animal; Disease Progression; Fluorescein; Gene Transfer Techniques; Genetic Vectors; Laser Coagulation; Light Coagulation; Luminescent Proteins; Macular Degeneration; Male; Mice; Mice, Inbred C57BL; Micelles; Microscopy, Fluorescence; Polymers
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/162022
• Institution: National University of Singapore

10.1371/journal.pone.0028560