GALC deletions increase the risk of primary Open-Angle Glaucoma: The role of mendelian variants in complex disease

GALC deletions increase the risk of primary Open-Angle Glaucoma: The role of mendelian variants in complex disease

10.1371/journal.pone.0027134

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Bibliographic Details
Main Authors:	Liu Y., Gibson J., Wheeler J., Kwee L.C., Santiago-Turla C.M., Akafo S.K., Lichter P.R., Gaasterland D.E., Moroi S.E., Challa P., Herndon L.W., Girkin C.A., Budenz D.L., Richards J.E., Allingham R.R., Hauser M.A.
Other Authors:	DUKE-NUS MEDICAL SCHOOL
Format:	Article
Published:	2019
Subjects:	aldehyde dehydrogenase 1 family member A2 cell protein ciliary rootlet coiled coil rootlletin protein eyes absent 1 homolog 1 protein galactosylceramidase RAS p21 protein activator 4 unclassified drug adult article comparative genomic hybridization controlled study copy number variation enzyme activity galactosylceramidase gene gene gene deletion gene function gene loss gene replication genetic association genetic risk genotype heterozygosity loss human open angle glaucoma real time polymerase chain reaction risk assessment single nucleotide polymorphism validation process genetic predisposition genetics Comparative Genomic Hybridization Galactosylceramidase Gene Deletion Genetic Predisposition to Disease Glaucoma, Open-Angle Humans Real-Time Polymerase Chain Reaction
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/162025
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Institution:	National University of Singapore

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