Structured Observations Reveal Slow HIV-1 CTL Escape

Structured Observations Reveal Slow HIV-1 CTL Escape

10.1371/journal.pgen.1004914

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Bibliographic Details
Main Authors:	Roberts H.E., Hurst J., Robinson N., Brown H., Flanagan P., Vass L., Fidler S., Weber J., Babiker A., Phillips R.E., McLean A.R., Frater J.
Format:	Article
Published:	Public Library of Science 2020
Subjects:	antiretrovirus agent epitope Gag protein Nef protein nef protein, Human immunodeficiency virus 1 Pol protein adult Article CD4 lymphocyte count CD8+ T lymphocyte controlled study cytotoxic T lymphocyte envelope gene female gag gene gene sequence HLA typing human human cell Human immunodeficiency virus 1 infection immune evasion incidence major clinical study male nef gene phylogenetic tree prevalence seroconversion structural gene survival rate genetics high throughput sequencing Human immunodeficiency virus 1 Human immunodeficiency virus infection immunology middle aged mutation Adult CD8-Positive T-Lymphocytes Epitopes, T-Lymphocyte Female Gene Products, gag High-Throughput Nucleotide Sequencing HIV Infections HIV-1 Humans Male Middle Aged Mutation nef Gene Products, Human Immunodeficiency Virus pol Gene Products, Human Immunodeficiency Virus T-Lymphocytes, Cytotoxic
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/165394
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Institution:	National University of Singapore

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Summary:	10.1371/journal.pgen.1004914