Role of Pirh2 in mediating the regulation of p53 and c-Myc

• Main Authors: Hakem A., Bohgaki M., Lemmers B., Tai E., Salmena L., Matysiak-Zablocki E., Jung Y.-S., Karaskova J., Kaustov L., Duan S., Madore J., Boutros P., Sheng Y., Chesi M., Bergsagel P.L., Perez-Ordonez B., Mes-Masson A.-M., Penn L., Squire J., Chen X., Jurisica I., Arrowsmith C., Sanchez O., Benchimol S., Hakem R.
• Other Authors: MEDICINE
• Format: Article
• Published: Public Library of Science 2020
• Subjects: Myc protein; Pirh2 protein; protein p53; ubiquitin protein ligase E3; unclassified drug; animal cell; animal tissue; article; breast cancer; cancer inhibition; cancer survival; carcinogenesis; cell hyperplasia; controlled study; DNA damage; embryo; human; human cell; in vivo study; lung cancer; mouse; nonhuman; ovary cancer; plasma cell hyperplasia; protein degradation; protein expression; protein function; protein interaction; protein stability; ubiquitination; Animals; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HEK293 Cells; Humans; Kaplan-Meier Estimate; Mice; Mice, Inbred C57BL; Neoplasms; Proteolysis; Proto-Oncogene Proteins c-myc; Radiation Tolerance; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases; Ubiquitination; Mus
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165411
• Institution: National University of Singapore

10.1371/journal.pgen.1002360