Toll-Like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease

• Main Authors: Budulac S.E., Boezen H.M., Hiemstra P.S., Lapperre T.S., Vonk J.M., Timens W., Postma D.S., Kauffman H.F., de Reus D., Jansen D.F., Barentsen M.D.W., Zeinstra-Smit M., Luteijn A.J., van der Molen T., ter Veen G., Gosman M.M.E., ten Hacken N.H.T., Kerstjens H.A.M., van Maaren M.S., Veltman C.A., Verbokkem A., Verhage I., Vink-Klooster H.K., Snoeck-Stroband J.B., Thiadens H., Sont J.K., Bajema I., Gast-Strookman J., Janssen K., Rabe K.F., van Schadewijk A., Smit-Bakker J., Stolk J., Tire' A.C.J.A., van der Veen H., Wijffels M.M.E., Willems L.N.A., Sterk P.J., Mauad T.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Public Library of Science 2020
• Subjects: toll like receptor 2; toll like receptor 4; adult; article; chronic obstructive lung disease; controlled study; cross-sectional study; disease severity; eosinophil count; female; forced expiratory volume; gene activation; gene expression regulation; gene frequency; genetic analysis; genetic association; genetic variability; heterozygote; homozygote; human; inflammatory cell; lung alveolus macrophage; major clinical study; male; molecular pathology; neutrophil count; receptor gene; single nucleotide polymorphism; sputum analysis; toll like receptor 2 gene; toll like receptor 4 gene; Bacteria (microorganisms)
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165567
• Institution: National University of Singapore

10.1371/journal.pone.0043124