Mechanism of cellular uptake and impact of ferucarbotran on macrophage physiology

• Main Authors: Yang C.-Y., Tai M.-F., Lin C.-P., Lu C.-W., Wang J.-L., Hsiao J.-K., Liu H.-M.
• Format: Article
• Published: Public Library of Science 2020
• Subjects: arsenosobenzene; ferucarbotran; ferumoxytol; reactive oxygen metabolite; superparamagnetic iron oxide nanoparticle; contrast medium; dextran; magnetite nanoparticle; nanoparticle; superparamagnetic iron oxide; animal cell; article; cell count; cell labeling; cell proliferation; cell tracking; cell transport; cell viability; concentration response; controlled study; correlation analysis; in vivo study; internalization; isotope labeling; macrophage function; mitochondrial membrane potential; mouse; nonhuman; nuclear magnetic resonance imaging; physical chemistry; protein synthesis; signal processing; signal transduction; animal; cell line; cell survival; chemistry; cytology; dose response; drug effect; endocytosis; flow cytometry; macrophage; methodology; monocyte; radiation scattering; spectrophotometry; time; Murinae; Animals; Cell Line; Cell Survival; Contrast Media; Dextrans; Dose-Response Relationship, Drug; Endocytosis; Flow Cytometry; Macrophages; Magnetite Nanoparticles; Mice; Monocytes; Nanoparticles; Reactive Oxygen Species; Scattering, Radiation; Spectrophotometry; Time Factors
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165587
• Institution: National University of Singapore

10.1371/journal.pone.0025524