Caveolin-1 influences vascular protease activity and is a potential stabilizing factor in human atherosclerotic disease

• Main Authors: Rodriguez-Feo J.A., Hellings W.E., Moll F.L., De Vries J.-P.P.M., van Middelaar B.J., Alegra A., Sluijter J., van der Broek T., Sessa W.C., De Kleijn D.P.V., Pasterkamp G.
• Other Authors: SURGERY
• Format: Article
• Published: Public Library of Science 2020
• Subjects: acetylsalicylic acid; beta adrenergic receptor blocking agent; caveolin 1; cyclooxygenase 2; dipeptidyl carboxypeptidase inhibitor; gelatinase B; high density lipoprotein cholesterol; hydroxymethylglutaryl coenzyme A reductase inhibitor; interleukin 6; interleukin 8; lipopolysaccharide; low density lipoprotein cholesterol; nonsteroid antiinflammatory agent; triacylglycerol; adult; aged; animal experiment; animal model; animal tissue; artery injury; artery intima proliferation; article; atherosclerosis; atherosclerotic plaque; cardiovascular disease; carotid artery obstruction; carotid endarterectomy; cholesterol blood level; controlled study; down regulation; enzyme activity; female; follow up; heart infarction; human; human tissue; incidence; macrophage; major clinical study; male; mouse; nonhuman; prognosis; protein expression; protein localization; restenosis; sex difference; swine; thrombosis; Western blotting; animal; carotid artery disease; genetics; immunohistochemistry; immunology; metabolism; Mus; Sus; Aged; Animals; Atherosclerosis; Carotid Artery Diseases; Caveolin 1; Follow-Up Studies; Humans; Immunohistochemistry; Interleukin-6; Interleukin-8; Male; Matrix Metalloproteinase 9; Mice
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165607
• Institution: National University of Singapore

10.1371/journal.pone.0002612