Sterile protection against malaria is independent of immune responses to the circumsporozoite protein

• Main Authors: Grüner A.C., Mauduit M., Tewari R., Romero J.F., Depinay N., Kayibanda M., Lallemand E., Chavatte J.-M., Crisanti A., Sinnis P., Mazier D., Corradin G., Snounou G., Rénia L.
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: Public Library of Science 2020
• Subjects: circumsporozoite protein; parasite antigen; circumsporozoite protein, Protozoan; protozoal protein; unclassified drug; animal experiment; animal model; article; controlled study; immune response; immunity; immunization; malaria; malaria control; mouse; nonhuman; Plasmodium berghei; Plasmodium falciparum; protein analysis; protein expression; protein function; protein targeting; radiation attenuation; sporozoite; transgenic organism; vaccine production; amino acid sequence; animal; Bagg albino mouse; chemistry; enzyme linked immunosorbent assay; fluorescent antibody technique; immunology; malaria falciparum; molecular genetics; sequence homology; Bacteria (microorganisms); Protozoa; Amino Acid Sequence; Animals; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Malaria, Falciparum; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Protozoan Proteins; Sequence Homology, Amino Acid
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165611
• Institution: National University of Singapore

10.1371/journal.pone.0001371