An economic evaluation of neonatal screening for inborn errors of metabolism using tandem mass spectrometry in Thailand

• Main Authors: Thiboonboon K., Leelahavarong P., Wattanasirichaigoon D., Vatanavicharn N., Wasant P., Shotelersuk V., Pangkanon S., Kuptanon C., Chaisomchit S., Teerawattananon Y.
• Other Authors: SAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
• Format: Article
• Published: Public Library of Science 2020
• Subjects: orphan drug; vitamin; isovaleryl coenzyme A dehydrogenase; Article; budget; clinical feature; controlled study; cost benefit analysis; cost effectiveness analysis; cost utility analysis; delayed diagnosis; disorders of carbohydrate metabolism; drug cost; early childhood intervention; early diagnosis; economic evaluation; health program; human; inborn error of metabolism; isovaleric acidemia; major clinical study; maple syrup urine disease; methylmalonic acidemia; money; newborn; newborn screening; outcome assessment; phenylketonuria; program cost effectiveness; propionic acidemia; quality adjusted life year; retrospective study; sensitivity and specificity; tandem mass spectrometry; Thailand; Amino Acid Metabolism, Inborn Errors; decision tree; deficiency; economic model; economics; Markov chain; Metabolism, Inborn Errors; Multiple Carboxylase Deficiency; multivariate analysis; Phenylketonurias; probability; reproducibility; Cost-Benefit Analysis; Decision Trees; Humans; Infant, Newborn; Isovaleryl-CoA Dehydrogenase; Maple Syrup Urine Disease; Markov Chains; Models, Economic; Multivariate Analysis; Neonatal Screening; Probability; Propionic Acidemia; Quality-Adjusted Life Years; Reproducibility of Results; Tandem Mass Spectrometry
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165686
• Institution: National University of Singapore

10.1371/journal.pone.0134782