Transcriptional repressor Tbx3 is required for the hormone-sensing cell lineage in mammary epithelium

• Main Authors: Kunasegaran K., Ho V., Chang T.H.-.T., De Silva D., Bakker M.L., Christoffels V.M., Pietersen A.M.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Public Library of Science 2020
• Subjects: estrogen receptor; transcription factor; transcription factor Tbx3; unclassified drug; uvomorulin; hormone; repressor protein; T box transcription factor; Tbx3 protein, mouse; adult; animal cell; animal tissue; Article; breast development; breast epithelium; cell lineage; cell type; E cadherin gene; female; flow cytometry; gene expression; gene expression regulation; gene silencing; gene targeting; hormone sensing cell; immunofluorescence; in vivo study; mammary gland; mouse; nonhuman; protein expression; stem cell; Tbx3 gene; transcription termination; aging; animal; cytology; drug effects; epithelium cell; fluorescence; genetic transcription; growth, development and aging; metabolism; newborn; reporter gene; udder; Aging; Animals; Animals, Newborn; Cell Lineage; Epithelial Cells; Female; Fluorescence; Genes, Reporter; Hormones; Mammary Glands, Animal; Mice; Receptors, Estrogen; Repressor Proteins; T-Box Domain Proteins; Transcription, Genetic
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165708
• Institution: National University of Singapore

10.1371/journal.pone.0110191