Prior exposure to inhaled allergen enhances anti-viral immunity and T cell priming by dendritic cells

• Main Authors: Lee D.C.P., Tay N.Q., Thian M., Prabhu N., Furuhashi K., Kemeny D.M.
• Other Authors: MICROBIOLOGY AND IMMUNOLOGY
• Format: Article
• Published: Public Library of Science 2020
• Subjects: allergen; animal extract; Blomia tropicalis extract; CD11b antigen; gamma interferon; unclassified drug; plant extract; adaptive immunity; allergic airway inflammation; animal cell; animal experiment; animal model; animal tissue; Article; asthma; Blomia tropicalis; C57BL 6 mouse; CD8+ T lymphocyte; cell selection; controlled study; cross presentation; cytokine production; dendritic cell; disease association; disease severity; drug sensitization; ex vivo study; female; goblet cell; histopathology; immune response; in vivo study; influenza; innate immunity; lung; lymph node; mouse; nonhuman; T lymphocyte; viral clearance; weight reduction; animal; biosynthesis; bronchoalveolar lavage fluid; C57BL mouse; complication; dose response; exposure; flow cytometry; immunology; Influenza A virus; orthomyxovirus infection; virology; virus load; Allergens; Animals; Asthma; Bronchoalveolar Lavage Fluid; Dendritic Cells; Dose-Response Relationship, Drug; Flow Cytometry; Inhalation Exposure; Interferon-gamma; Lung; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections; Plant Extracts; T-Lymphocytes; Viral Load
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165767
• Institution: National University of Singapore

10.1371/journal.pone.0190063