Site-specific phosphorylation of casein kinase 1δ(CK1δ) regulates its activity towards the circadian regulator PER2

• Main Authors: Eng G.W.L., Edison, Virshup D.M.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Public Library of Science 2020
• Subjects: casein kinase Idelta; cycline; dinaciclib; PER2 protein; proline; staurosporine; circadian rhythm signaling protein; PER2 protein, human; serine; threonine; animal cell; Article; cell cycle; circadian rhythm; controlled study; embryo; enzyme activity; enzyme regulation; extracellular space; intracellular signaling; luciferase assay; mouse; nonhuman; protein degradation; protein domain; protein phosphorylation; protein stability; signal transduction; binding site; chemistry; gene expression regulation; genetics; HEK293 cell line; human; metabolism; mutation; phosphorylation; Binding Sites; Casein Kinase Idelta; Cell Cycle; Gene Expression Regulation; HEK293 Cells; Humans; Mutation; Period Circadian Proteins; Phosphorylation; Protein Stability; Serine; Signal Transduction; Threonine
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165794
• Institution: National University of Singapore

10.1371/journal.pone.0177834