A novel approach to adenine-induced chronic kidney disease associated anemia in rodents

• Main Authors: Rahman A., Yamazaki D., Sufiun A., Kitada K., Hitomi H., Nakano D., Nishiyama A.
• Other Authors: DUKE-NUS MEDICAL SCHOOL
• Format: Article
• Published: Public Library of Science 2020
• Subjects: adenine; alpha smooth muscle actin; creatinine; erythropoietin; fibroblast growth factor 23; hemoglobin; recombinant erythropoietin; anemia; animal experiment; animal model; animal tissue; Article; chronic kidney failure; controlled study; creatinine blood level; disease association; disease severity; female; ferritin blood level; Fgf23 gene; gamma glutamyl transferase blood level; gene expression; hematocrit; hemoglobin blood level; kidney fibrosis; kidney injury; kidney structure; male; mouse; nonhuman; protein blood level; rat; Sma gene; urea nitrogen blood level; animal; blood; C57BL mouse; chemically induced; complication; dose response; drug effects; kidney; metabolism; pathology; pathophysiology; Wistar rat; Adenine; Anemia; Animals; Blood Urea Nitrogen; Creatinine; Dose-Response Relationship, Drug; Erythropoietin; Hematocrit; Hemoglobins; Kidney; Kidney Failure, Chronic; Male; Mice; Mice, Inbred C57BL; Rats; Rats, Wistar
• Online Access: https://scholarbank.nus.edu.sg/handle/10635/165970
• Institution: National University of Singapore

10.1371/journal.pone.0192531